Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. Visit your doctor regularly. HbA1c levels from baseline throughout a one-year study in patients with type 2 diabetes mellitus when used in combination with: A diet alone; B sulfonylurea; C metformin; or D insulin. When used alone, Precose does not cause low blood glucose hypoglycemia. If used in combination with some diabetes medications hypoglycemia may occur. Acarbose is also contraindicated in patients with inflammatory bowel disease, colonic ulceration, partial intestinal obstruction, or in patients predisposed to intestinal obstruction. buy sumatriptan shop uk
I'm already on ALA and when my bottle runs out next week yes, will be one of the first people trying out the r-ala. You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages because they can increase the risk of developing low blood sugar. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs including any herbal medicines or supplements or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.
Acarbose Tablets should be adjusted at 4-8 week intervals based on one-hour postprandial glucose or glycosylated hemoglobin levels, and on tolerance. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking acarbose, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Digestive Tract: Gastrointestinal symptoms are the most common reactions to Acarbose Tablets. Acarbose Tablets themselves do not cause hypoglycemia even when administered to patients in the fasted state. Sulfonylurea drugs and insulin, however, can lower blood sugar levels enough to cause symptoms or sometimes life-threatening hypoglycemia. Because Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood sugar, it may increase the hypoglycemic potential of these agents. Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, and no increased incidence of hypoglycemia was observed in patients when Acarbose Tablets were added to metformin therapy. The risk of hypoglycemia, its symptoms and treatment, and conditions that predispose to its development should be well understood by patients and responsible family members.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Your doctor may need to adjust your anti-diabetic medication, exercise program, or diet. Many people find that taking steps like these greatly reduces symptoms of dumping syndrome. Lack of interaction between thioctic acid, glibenclamide and acarbose. Other family members need to learn how to prevent side effects or help with side effects if they occur. Also, patients with diabetes may need special counseling about diabetes medicine dosing changes that might occur because of lifestyle changes, such as changes in exercise and diet. Furthermore, counseling on contraception and pregnancy may be needed because of the problems that can occur in patients with diabetes during pregnancy. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Also watch for signs of high blood sugar hyperglycemia such as increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; bloody stools; severe or persistent diarrhea or constipation; severe stomach pain; unusual bleeding or bruising. Cut food into very small pieces. Chew well before swallowing. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Always keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon emergency injection kit and tell you how to give the injection. Be sure your family and close friends know how to help you in an emergency.
If symptoms of low blood sugar occur, eat glucose tablets or gel or honey, or drink fruit juice to relieve the symptoms. Table sugar sucrose or regular nondiet soft drinks will not work. Also, check your blood for low blood sugar. Glucagon is used in emergency situations when severe symptoms such as seizures convulsions or unconsciousness occur. Precose slows the digestion of carbohydrate sugars and starches in the small intestine. What is the most important information I should know about acarbose Precose? Discuss the risks and benefits with your doctor. Patients Receiving Sulfonylureas or Insulin: Sulfonylurea agents or insulin may cause hypoglycemia. Acarbose Tablets given in combination with a sulfonylurea or insulin may cause a further lowering of blood glucose and may increase the potential for hypoglycemia. If hypoglycemia occurs, appropriate adjustments in the dosage of these agents should be made. Stop eating when you first begin to feel full. Patients Receiving Sulfonylureas or Insulin: Sulfonylurea agents or insulin may cause hypoglycemia. Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood glucose and may increase the potential for hypoglycemia. If hypoglycemia occurs, appropriate adjustments in the dosage of these agents should be made. If you take acarbose with insulin or other diabetes medications, your blood sugar could get too low. Water pulled out of the bloodstream moves into the small intestine. ponstel
Acarbose is to be used only by the patient for whom it is prescribed. Do not share it with other people. Do not share this medication with others. What happens if I overdose Precose? Macrovascular Outcomes: There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with Acarbose Tablets or any other anti-diabetic drug. Geriatric Use: Of the total number of subjects in clinical studies of Acarbose Tablets in the United States, 27% were 65 and over, while 4% were 75 and over. No overall differences in safety and effectiveness were observed between these subjects and younger subjects. Hypoglycemia: Because of their mechanism of action, Acarbose Tablets when administered alone should not cause hypoglycemia in the fasted or postprandial state. Sulfonylurea agents or insulin may cause hypoglycemia. Because Acarbose Tablets given in combination with a sulfonylurea or insulin will cause a further lowering of blood glucose, it may increase the potential for hypoglycemia. Hypoglycemia does not occur in patients receiving metformin alone under usual circumstances of use, and no increased incidence of hypoglycemia was observed in patients when Acarbose Tablets were added to metformin therapy. Oral glucose dextrose whose absorption is not inhibited by Acarbose Tablets, should be used instead of sucrose cane sugar in the treatment of mild to moderate hypoglycemia. Sucrose, whose hydrolysis to glucose and fructose is inhibited by Acarbose Tablets, is unsuitable for the rapid correction of hypoglycemia. Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. It is not known whether acarbose passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using acarbose. epogen in malaysia epogen
Higher income. Career mobility. If one is available, read the Medication Guide before your start taking this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Acarbose Tablets are contraindicated in patients with known hypersensitivity to the drug. Acarbose Tablets are contraindicated in patients with diabetic ketoacidosis or cirrhosis. Acarbose Tablets are also contraindicated in patients with inflammatory bowel disease, colonic ulceration, partial intestinal obstruction or in patients predisposed to intestinal obstruction. In addition, Acarbose Tablets are contraindicated in patients who have chronic intestinal diseases associated with marked disorders of digestion or absorption and in patients who have conditions that may deteriorate as a result of increased gas formation in the intestine. During treatment initiation and dose titration see below one-hour postprandial plasma glucose may be used to determine the therapeutic response to Acarbose Tablets and identify the minimum effective dose for the patient. Thereafter, glycosylated hemoglobin should be measured at intervals of approximately three months. The therapeutic goal should be to decrease both postprandial plasma glucose and glycosylated hemoglobin levels to normal or near normal by using the lowest effective dose of Acarbose Tablets, either as monotherapy or in combination with sulfonylureas, insulin or metformin. Your doctor may want you to stop taking acarbose for a short time if you become ill, have a fever or infection, or if you have surgery or a medical emergency. Keep all medicines away from children and pets. If you take acarbose with insulin or other diabetes medications, your blood sugar could get too low. Low blood sugar hypoglycemia can occur if you skip a meal, exercise too long, drink alcohol, or are under stress. Acarbose Tablets as monotherapy or in combination with sulfonylurea, metformin or insulin treatment was conducted in Canada in which 316 patients were included in the primary efficacy analysis Figure 2. In the diet, sulfonylurea and metformin groups, the mean decrease in HbA1c produced by the addition of Acarbose Tablets was statistically significant at six months, and this effect was persistent at one year. In the Acarbose Tablets-treated patients on insulin, there was a statistically significant reduction in HbA1c at six months, and a trend for a reduction at one year. This medication should not be used if you have certain medical conditions. can buy escitalopram uk
Loss of Control of Blood Glucose: When diabetic patients are exposed to stress such as fever, trauma, infection, or surgery, a temporary loss of control of blood glucose may occur. At such times, temporary insulin therapy may be necessary. Do not take more capsules in a day than prescribed by your doctor. Your condition will not improve any faster, and your risk of side effects will increase. Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. You should take the prescribed dose with the FIRST BITE of each main meal. A small dose will be started and your health care provider will gradually increase it as needed. Your health care provider may want you to combine Precose with another type of diabetes pill. Since Precose works differently than the other diabetes pills, it will not interfere with their action. Combined with these pills, Precose may further improve your control. All medicines may cause side effects, but many people have no, or minor, side effects. Carefully follow the regular testing of urine or blood glucose schedules given to you by your health care provider. For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products. AIMS: Thioctic acid TA glibenclamide and acarbose are widely used to either alone or concomitantly treat patients suffering from noninsulin-dependent diabetes NIDDM. This study systematically investigated drug-drug interactions between TA and glibenclamide and TA and acarbose. METHODS: Fourteen male and 10 female healthy volunteers participated a randomized, open three period cross over trial treatments A-C followed by a fourth period treatment D. A baseline profile for plasma insulin and glucose concentrations, variables which served as pharmacodynamic measures, was assessed before entering the trial. What should I avoid while taking acarbose Precose? After gastric surgery, it can be more difficult to regulate movement of food, which dumps too quickly into the small intestine. Eating certain foods makes dumping syndrome more likely. For example, refined sugars rapidly absorb water from the body, causing symptoms. Symptoms may also happen after eating dairy products and certain fats or fried foods. Also avoid dairy products and alcohol. And avoid eating solids and drinking liquids during the same meal. In fact, don't drink 30 minutes before and 30 minutes after meals. Adding the a-glucosidase inhibitor, Bayer Corp. opux.info propecia
The cause of this rapid swing in may be worse when eating sweets or other simple carbohydrates. If you also take charcoal or digestive enzyme preparations eg, amylase, pancreatin ask your doctor or pharmacist how to take them with acarbose. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Acarbose is used to treat type 2 diabetes. Acarbose is sometimes used in combination with insulin or other diabetes medications you take by mouth. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Take acarbose by mouth at the start with the first bite of each main meal. Do not change brands or dosage forms of without consulting your doctor or pharmacist. Acarbose may also be used for purposes not listed in this medication guide. Choose from Top Nursing Uniform Companies. All sizes, styles and popular name brands available. If you finish a meal and you have forgotten to take the medicine, do not take the missed dose. Instead, take the next dose at the beginning of your next meal, as scheduled. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment.
In a study of 6 healthy men, less than 2% of an oral dose of Acarbose was absorbed as active drug, while approximately 35% of total radioactivity from a 14C-labeled oral dose was absorbed. An average of 51% of an oral dose was excreted in the feces as unabsorbed drug-related radioactivity within 96 hours of ingestion. Because Acarbose acts locally within the gastrointestinal tract, this low systemic bioavailability of parent compound is therapeutically desired. Following oral dosing of healthy volunteers with 14C-labeled Acarbose, peak plasma concentrations of radioactivity were attained 14-24 hours after dosing, while peak plasma concentrations of active drug were attained at approximately 1 hour. The delayed absorption of Acarbose-related radioactivity reflects the absorption of metabolites that may be formed by either intestinal bacteria or intestinal enzymatic hydrolysis. Take the missed dose as soon as you remember be sure to take it with a meal. If it has been longer than 15 minutes since you started your meal, you may still take acarbose but it may be less effective than taking it with the first bite of the meal. Do not take acarbose between meals, and do not take extra medicine to make up a missed dose. What happens if I overdose? Check with your pharmacist about how to dispose of unused medicine. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding. If swallowing is difficult, then the capsule may be opened and the contents mixed in a small amount of liquid or soft food that does not need to be chewed such as room-temperature applesauce. Do not mix the contents of the capsule with alkaline food or liquid such as milk, ice cream, tea. PrecoseR acarbose tablets to existing therapies for patients with type II diabetes improves long-term blood glucose control, according to final results of the United Kingdom Prospective Diabetes Study. Your pharmacist can provide more information about acarbose. How should I take acarbose Precose? microzide how to order shop
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Mostly you will be prescribed one 500mg Glycomet Generic Glucomin tablet 3 times a day, while the 850mg tablets are usually taken twice daily to give effective diabetes control. You should use Glycomet Generic Glucomin only as directed by your doctor. In contrast to sulfonylureas, Acarbose Tablets do not enhance insulin secretion. The antihyperglycemic action of Acarbose results from a competitive, reversible inhibition of pancreatic alpha-amylase and membrane-bound intestinal alpha-glucoside hydrolase enzymes. Pancreatic alpha-amylase hydrolyzes complex starches to oligosaccharides in the lumen of the small intestine, while the membrane-bound intestinal alpha-glucosidases hydrolyze oligosaccharides, trisaccharides, and disaccharides to glucose and other monosaccharides in the brush border of the small intestine. In diabetic patients, this enzyme inhibition results in a delayed glucose absorption and a lowering of postprandial hyperglycemia. The beans are all very fibrous, complex carbs and release the sugars very slowly - stick to the ribs as they say. Precose decreases peaks in blood glucose levels that occur after eating by delaying absorption of carbohydrates sugar and starches into the bloodstream. Take at the start with first bite of each main meal; patients should be adhering to a diabetic diet to minimize GI side effects. Diabetes patients - Carry an ID card at all times that says you have diabetes. Check your blood sugar levels as directed by your doctor. If they are often higher than they should be and you take acarbose exactly as prescribed, tell your doctor. The fraction of Acarbose that is absorbed as intact drug is almost completely excreted by the kidneys. When Acarbose was given intravenously, 89% of the dose was recovered in the urine as active drug within 48 hours. In contrast, less than 2% of an oral dose was recovered in the urine as active that is, parent compound and active metabolite drug. This is consistent with the low bioavailability of the parent drug. The plasma elimination half-life of Acarbose activity is approximately 2 hours in healthy volunteers. Where can I get more information? Its action is quite different from sulfonylureas and metformin. By slowing the digestion of carbohydrates in the small intestine, the blood sugar rise after a meal is lessened. Acarbose works by inhibiting enzymes in the intestine that break carbohydrates down, so glucose levels rise more slowly and the person's own internal production of insulin can more easily respond. You may be more likely to have hyperglycemia high blood sugar if you are taking acarbose with other drugs that raise blood sugar. Take this medication by mouth, usually 3 times a day at the start with the first bites of each main meal or as directed by your doctor. generic epivir discussion
If no further reduction in postprandial glucose or HbA1c is observed with titration to 100 mg three times a day, consider lowering the dose. If you miss a dose of acarbose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Symptoms of high blood sugar include blurred vision; drowsiness; dry mouth; flushed, dry skin; fruit-like breath odor; increased urination; ketones in urine; loss of appetite; stomachache, nausea, or vomiting; tiredness; troubled breathing rapid and deep; unconsciousness; or unusual thirst. In the 59 cases where follow-up was recorded, hepatic abnormalities improved or resolved upon discontinuation of Acarbose Tablets in 55 and were unchanged in two. Cases of fulminant hepatitis with fatal outcome have been reported; the relationship to Acarbose is unclear. Severe hypoglycemia may require the use of either intravenous glucose infusion or glucagon injection. Avoid taking a digestive enzyme such as pancreatin, amylase, or lipase at the same time you take acarbose. These enzymes can make it harder for your body to absorb acarbose. Products that contain digestive enzymes include Arco-Lase, Cotazym, Donnazyme, Pancrease, Creon, and Ku-Zyme. Use this medication regularly to get the most benefit from it. Take it with every meal or snack. This list is not complete and other drugs may affect your blood sugar or interact with acarbose. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Some medical conditions may interact with acarbose. Acarbose corresponding to 10 times the dose in man, based on body surface area showed no evidence of embryotoxicity and there was no evidence of teratogenicity at a dose 32 times the dose in man based on body surface area. There are, however, no adequate and well-controlled studies of Acarbose Tablets in pregnant women. Because animal reproduction studies are not always predictive of the human response, this drug should be used during pregnancy only if clearly needed. Because current information strongly suggests that abnormal blood glucose levels during pregnancy are associated with a higher incidence of congenital anomalies as well as increased neonatal morbidity and mortality, most experts recommend that insulin be used during pregnancy to maintain blood glucose levels as close to normal as possible. Use sugar replacements, such as Splenda, Equal, or Sweet'N Low, instead of sugar. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and close friends know how to help you in an emergency. Unlike sulfonylureas or insulin, an overdose of Acarbose Tablets will not result in hypoglycemia. An overdose may result in transient increases in flatulence, diarrhea, and abdominal discomfort which shortly subside. In cases of overdosage the patient should not be given drinks or meals containing carbohydrates polysaccharides, oligosaccharides and disaccharides for the next 4-6 hours. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Keep a recent prescription and your medical history with you. Be prepared for an emergency as you would normally. Make allowances for changing time zones and keep your meal times as close as possible to your usual meal times. clavaseptin
Some MEDICINES MAY INTERACT with acarbose. There may be a time when you need emergency help for a problem caused by your diabetes. You need to be prepared for these emergencies. It is a good idea to wear a medical identification ID bracelet or neck chain at all times. Also, carry an ID card in your wallet or purse that says that you have diabetes and a list of all of your medicines. The small intestine stretches. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. About FAERS: The FDA Adverse Event Reporting System FAERS is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. alavert
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Symptoms of high blood sugar hyperglycemia include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your doctor right away. Your dosage may need to be increased or you may need other drugs. A1c, complete blood counts should be performed periodically to check for side effects and monitor your response to therapy. Check your blood or urine sugar levels regularly as directed by your doctor or pharmacist. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Sorry I couldn't provide a more sound scientific basis, but there are foods around that are not expensive, not genetically engineered, and provided very stable carbohydrate management without having to use a myriad of advanced concoctions.
Renal Impairment: Plasma concentrations of Acarbose Tablets in renally impaired volunteers were proportionally increased relative to the degree of renal dysfunction. Do not use this medication if you are allergic to acarbose, or if you are in a state of diabetic ketoacidosis call your doctor for treatment with insulin. You also should not use acarbose if you have inflammatory bowel disease, an ulcer or blockage in your intestines, or cirrhosis of the liver. Drink liquids 30 to 45 minutes after meals. Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.
The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs. Using acarbose with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Your doctor may substitute insulin for this drug during your pregnancy. Follow all instructions carefully.
Take exactly as prescribed by your Health Provider. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately: chest pain, rash. An early dumping phase may happen about 30 to 60 minutes after you eat. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products.